Participants in the microdosing study (using LSD, 1p-LSD, or mushrooms) have reported using these medications and supplements with no adverse response. If you are looking for a medication or supplement of interest, we recommend using CTRL+F to find it.
hydrocodone (Vicodin, Norco)
ibuprofen (Advil, Motrin)
heart/high blood pressure medication
amiodarone (Cordarone, Nexterone)
Hydrochlorothiazide (HCTZ, HCT)
lisinopril (Prinivil, Zestril)
telemisartin (Micardis, Actavis)
clindamycin (Cleocin, Dalacin, Clinacin)
minocycline (Minocin, Minomycin, Akamin)
fluconazole (Diflucan, Celozole)
Focus meds (ADHD/ADD)
dextroamphetamine (Dexedrine, Metamina, Attentin, Zenzedi, Procentra, Amfexa)
methylphenidate (Ritalin, Biphentin)
zopiclone (Zimovane, Imovane)
zolpidem (ambien, stilnox)
diphenahydramine (Benadryl, Gravol)
Benzodiazepines (Anxiety, sleep, seizure)
Mood stabilizers and antipsychotics
methimazole or thiamazole
Breathing (asthma, COPD)
beclometasone (Clenil Modulite)
Drugs of recreation
Alcohol dependence treatment
Hormones and Steroids
Norethindrone Acetate ethinyl estradiol
prednisone (Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone)
progesterone (Prometrium, Utrogestan, Endometrin)
methyl sulfonyl methane (MSM)
st. johns wort
“If you are looking for free, confidential peer support during or after a psychedelic experience, please contact Fireside Project by calling or texting 6-2FIRESIDE (623-473-7433).”
Psychedelics are not well studied, and the long term effect of them are not well-known While we believe the prevailing view in the scientific community is that psychedelics are not inherently dangerous, there are documented risks and legal exposure to buying and using them. As always, do your own research and rely upon a variety of recognized sources of unbiased information before taking any psychedelic drug.
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By Annie Stuart Medically Reviewed by Christine Mikstas, RD, LD on May 20, 2021
Reishi mushrooms are among several medicinal mushrooms that have been used for hundreds of years, mainly in Asian countries, for treatment of infections. More recently, they have also been used in the treatment of pulmonary diseases and cancer. Medicinal mushrooms have been approved adjuncts to standard cancer treatments in Japan and China for more than 30 years and have an extensive clinical history of safe use as single agents or combined with chemotherapy.
The reishi mushroom is also known as lingzhi.
There is some scientific evidence of its effectiveness, including lab research and some small human studies. Researchers are beginning to look at the chemical makeup of this mushroom to better understand how and whether it really works for each of these conditions.
Doses may depend upon factors that include:
But each of these is a typical oral daily dose:
Reishi mushroom is cultivated and sold as a food, but it may be tough and bitter.
When taken for health reasons, it is usually dried or taken as an extract, such as in the form of:
Side effects. When used over three to six months, reishi mushroom can cause an allergic reaction associated with dryness in your:
It can also cause:
Risks. Taking reishi mushroom may be riskier if you have low blood pressure or are taking therapy to raise your blood pressure, are taking diabetes medications, or have immune system disorders or medications.
Higher doses of reishi mushroom might make bleeding more likely in people who have a very low platelet count.
Interactions. Reishi mushroom may increase the risk of bleeding. Talk to your doctor before taking reishi mushroom if you are using anticoagulant or antiplatelet drugs such as:
Reishi mushroom may also interact with high blood pressure medications.
Tell your doctor about any supplements you're taking, even if they're natural. That way, your doctor can check on any potential side effects or interactions with medications or foods. They can let you know if the supplement might raise your risk.
The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Unlike drug manufacturers, the makers of supplements don’t have to show their products are safe or effective before selling them on the market.
WebMD Medical Reference